Platelets are Hyperactivated but Show Reduced Glycoprotein VI Reactivity in COVID-19 Patients
نویسندگان
چکیده
منابع مشابه
Differential effects of reduced glycoprotein VI levels on activation of murine platelets by glycoprotein VI ligands.
We have investigated the effects of decreased levels of the complex between glycoprotein VI (GPVI) and the Fc receptor gamma-chain (FcRgamma) on responses to collagen and GPVI-specific ligands in murine platelets. We show that levels of GPVI-FcRgamma of the order of 50% and 20% of wild-type levels caused 2- and 5-fold shifts to the right respectively in the dose-response curve for aggregation i...
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ژورنال
عنوان ژورنال: Thrombosis and Haemostasis
سال: 2021
ISSN: 0340-6245,2567-689X
DOI: 10.1055/a-1347-5555